Epinephrine in the Central Nervous System
by Stolk, Jon M.; U'Prichard, David C.; Fuxe, KjellFormat: Hardcover
Pub. Date: 1988-03-24
Publisher(s): Oxford University Press
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Summary
Long thought to be unimportant in central nervous system activity, epinephrine is now known to play a key role in the brain's regulation of blood pressure, cardiovascular function, and other autonomic activities. This encyclopedic volume, written by leading international researchers, offers a comprehensive account of the chemical neuroanatomy, genetics, chemistry, and pharmacology of CNS epinephrine and its effects on behavior and autonomic function.
Table of Contents
| Historical Overview | |
| Following the Trail of Epinephrine from the Periphery to the Brain | |
| The Changing Face of Research on Epinephrine | |
| Morphology of Brain Epinephrine Systems | |
| Central Phenylethanolamine N-Methyltransferase-Immunoreactive Neurons: Distribution, Projections, Fine Structure, Ontogeny and Coexisting Peptides | |
| Morphometric Studies of Epinephrine and Neuropeptide Y (NPY) Costoring Neurons in the Rat Brain | |
| Mapping the Alpha Adrenergic Receptor in the Central Nervous System: A Guide to Structure and Function | |
| Connectivity and Ultrastructure of Nonadrenergic and Adrenergic Neurons in the Medulla Oblongata | |
| Regulation and Genetics of Adrenergic Systems | |
| Inheritance of Epinephrine Formation Rates and Phenylethanolamine N-Methyltransferase Structural Heterology in Inbred Rat Strains | |
| Molecular Basis for the Difference in Buffalo and Fischer Rat PNMT Expression | |
| Steroid Control of Neurotransmitter Synthesis: Glucocorticoid Regulation of Phenylethanolamine N-Methyltransferase | |
| Brain Epinephrine in Hypertension and Stress | |
| Pharmacological Approaches to Adrenergic Systems | |
| Approaches to the Design of Selective Inhibitors of Phenylethanolamine N-Methyltransferase (PNMT): Development of an Active Site Model for PNMT | |
| Biochemical Pharmacology of Brain Epinephrine Neurons: Comparison with Nonephinephrine Neurons | |
| Regulation of Anterior Pituitary Hormone Secretion by Brain Epinephrine | |
| Epinephrine and CRF Stimulate ACTH Release and Proopiomelanocortin Gene Expression | |
| Central Epinephrine Neurons and Alpha-2 Adrenoceptors | |
| Modulation of Epinephrine Release from Adrenal Medulla by Gamma-Aminobutyric Acid | |
| Brain and Peripheral Adrenoceptors | |
| Subtypes of Alpha-2 Adrenoceptors in Human and Rat Brain | |
| Agonist-Regulated Metabolism of Alpha- and Beta-Adrenoceptors | |
| Functional Association Between Epinephrine Neurons and Alpha-2 Adrenoceptors in Discrete Brain Areas: Analysis in Inbred Rat Strains | |
| Regulation of Brain Stem and Platelet Alpha-2 Adrenoceptors | |
| The Beta-Adrenergic Receptor-Coupled Adenylate Cyclase System | |
| Modification of Guanine Nucleotide Actions on Receptors and Adenylate Cyclase | |
| Central and Peripheral Alpha-2 and Beta Adrenoceptor Changes Induced by Antidepressant Treatments | |
| Adrenergic Neuron Electrophysiology and Behavior | |
| Inhibitory Synaptic Transmission Mediated by Catecholamines | |
| Bulbospinal Epinephri | |
| Table of Contents provided by Publisher. All Rights Reserved. |
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