Preface |
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vii | |
CHAPTER 1 Accident Prevention and First Aid |
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1 | (8) |
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1 | (3) |
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4 | (5) |
CHAPTER 2 Environmentally Responsible Handling of Chemicals and Solvents |
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9 | (10) |
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2.1 Dangerous Materials: Poisons, Laws, Regulations and Classes |
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10 | (1) |
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2.2 EU Poison Regulations |
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10 | (3) |
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13 | (1) |
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14 | (5) |
CHAPTER 3 Crystallisation |
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19 | (8) |
CHAPTER 4 Distillation |
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27 | (10) |
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4.1 Some Theoretical Considerations |
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28 | (2) |
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4.2 Distillation in Practice |
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30 | (7) |
CHAPTER 5 Chromatographic Methods |
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37 | (18) |
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37 | (3) |
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5.2 Analytical and Preparative Thin—Layer Chromatography |
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40 | (2) |
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5.3 Column Chromatography |
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42 | (7) |
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5.4 Rapid Column Chromatography |
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49 | (2) |
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51 | (4) |
CHAPTER 6 Extraction and Isolation |
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55 | (8) |
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6.1 Separation of Mixtures According to Acidity |
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56 | (7) |
CHAPTER 7 Structure Determination Using Spectroscopic Methods |
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63 | (10) |
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7.1 Infrared Spectroscopy (IR) |
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63 | (1) |
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7.2 Mass Spectrometry (MS) |
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64 | (1) |
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7.3 Nuclear Magnetic Resonance Spectroscopy (NMR) |
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64 | (1) |
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7.4 Ultraviolet and Visible Spectroscopy (UV/VIS) |
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64 | (9) |
CHAPTER 8 Searching the Chemical Literature |
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73 | (38) |
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8.1 The Information Mountain |
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73 | (1) |
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74 | (1) |
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74 | (31) |
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105 | (2) |
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8.5 Monographs, Reference Works and Handbooks |
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107 | (1) |
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108 | (3) |
CHAPTER 9 Laboratory Notebooks |
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111 | (4) |
CHAPTER 10 Writing a Report |
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115 | (4) |
CHAPTER 11 Example of a Laboratory Report |
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119 | (4) |
CHAPTER 12 Hints on the Synthesis of Organic Compounds |
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123 | (24) |
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12.1 The Route to Success |
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123 | (6) |
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12.2 Some Tips on Handling Water- and Air-Sensitive Substances |
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129 | (7) |
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12.3 Hints on Working at Low Temperatures |
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136 | (2) |
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12.4 Hints on the Synthesis and Analysis of Chiral Compounds |
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138 | (2) |
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12.5 Hints on the Synthesis of Isotopically Labelled Compounds |
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140 | (7) |
CHAPTER 13 Disposal and Destruction of Dangerous Materials |
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147 | (12) |
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13.1 Classification of Waste Material |
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148 | (1) |
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13.2 Environmentally Acceptable Substances for Treating Dangerous Materials in the Laboratory |
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149 | (1) |
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13.3 Special Instructions for the Destruction of the Main Classes of Dangerous Substances |
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149 | (6) |
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13.4 Deactivation of Unknown Laboratory Chemicals |
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155 | (1) |
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156 | (3) |
CHAPTER 14 Purification and Drying of Solvents |
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159 | (26) |
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160 | (5) |
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165 | (20) |
CHAPTER 15 EU R and S Phrases |
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185 | (8) |
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15.1 R Phrases: Indication of Particular Risks |
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185 | (2) |
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15.2 Combinations of R Numbers |
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187 | (2) |
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15.3 S Phrases: Indication of Safety Precautions |
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189 | (2) |
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15.4 Combinations of S Numbers |
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191 | (2) |
Index |
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193 | |